dinnes@nwbio.com, Les Goldman NWBO Stock Daily Chart The Company will remain blinded throughout this period and will not become unblinded until the independent statisticians deliver the initial results to the Company. CONTACTS “We are hopeful that DCVax®-L can become an important new treatment option for patients who urgently need more and better treatments for Glioblastoma brain cancer.”, “We are grateful to the independent service firms and the clinical trial sites who have worked so hard to complete the data collection and confirmation during many months of COVID restrictions and challenges,” Ms. lgoldman@nwbio.com. Finally, on Oct. 5, 2020, NWBO declared that data from the phase 3 study has been locked. BETHESDA, Md., Oct. 5, 2020 /PRNewswire/ -- Northwest Biotherapeutics (OTCQB: NWBO) ("NW Bio"), a biotechnology company developing DCVax(®) personalized immune therapies for … Neither the Company nor any party other than the independent statisticians will have access to any unblinded data at this stage. I surmise that this would deal with how long patients in the trial are surviving. We cannot guarantee that we actually will achieve the plans, intentions or expectations disclosed in our forward-looking statements and you should not place undue reliance on our forward-looking statements. However, the CRO and the Company are working intensively with these vendors on a continuous basis to move as quickly as possible. Northwest Biotherapeutics, Inc (OTCMKTS: NWBO) is once again in full beast mode skyrocketing up the charts on a massive surge of volume as investors eagerly await top line data from the Phase III trial of DCVax®-L. 804-513-4758 The primary endpoint of the trial is “Progression Free Survival,” meaning the length of time that a patient continues without disease progression (i.e., … DCVax-L at Phase 3 and DCVax-Direct will soon to move to Phase 2 in the clinic. Additional information on the foregoing risk factors and other factors, including Risk Factors, which could affect the Company’s results, is included in its SEC filings. All of the Trial sites are now finished. Finally, there may be other factors not mentioned above or included in the Company’s SEC filings that may cause actual results to differ materially from those projected in any forward-looking statement. One of them Northwest Biotherapeutics (OTC: NWBO) attempts to reach $3 after beating the record-high $2.30 price in October. BETHESDA, Md., July 24, 2020 /PRNewswire/ -- Northwest Biotherapeutics, Inc. (OTCQB: NWBO) ("NW Bio"), a biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, today announced that the data collection from all of the clinical trial sites for the Company's Phase 3 trial of DCVax®-L for Glioblastoma brain cancer (the "Trial") has been completed … For other analyses, it has been necessary to have the analyses done by two separate experts as a cross-check. Phone: 240-497-9024, DCVax® – L Phase III for GBM Brain Cancer, DCVax® – Direct Phase I/II for All Types of Inoperable Solid Tumor Cancers, Northwest Biotherapeutics Announces Data Lock of Phase III Trial. We cannot guarantee that we actually will achieve the plans, intentions or expectations disclosed in our forward-looking statements and you should not place undue reliance on our forward-looking statements. Reaching these personal sign-offs by each lead investigator at each of the Trial sites has been a key focus of activity towards data lock for the last couple of months, especially during June and July. Such analyses include, for example, genetic profiles such as IDH mutations. Statements made in this news release that are not historical facts, including statements concerning future treatment of patients using DCVax and future clinical trials, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Standard therapy for glioblastoma includes surgery, radiotherapy, and temozolomide. Actual results may differ materially from those projected in any forward-looking statement. Speculation is high that NWBO is … BETHESDA, Md., October 5, 2020 – Northwest Biotherapeutics (OTCQB: NWBO) (“NW Bio”), a biotechnology company developing DCVax® personalized immune therapies for solid tumor cancers, today announced that the database for the Phase III trial of DCVax®-L for Gliobastoma has been locked. When the Company receives the initial results, it will review the data and results with its Scientific Advisory Board, the Trial Steering Committee, and other key advisors. As DCVax is under Phase 3 trial the stock may move with volatility until the results come out in near future. BETHESDA - Northwest Biotherapeutics (OTCQB: NWBO) ('NW Bio'), a biotechnology company developing DCVax personalized immune therapies for solid tumor cancers, today announced that the data collection from all of the clinical trial sites for the Company's Phase 3 trial of DCVax-L for Glioblastoma brain cancer (the 'Trial') has been completed and all of the sites have signed off on the locking of their data. As noted in the Company's prior reports, in order to reach overall data lock for the Trial, each site's data must go through final collection, review, checking for queries, resolution of queries preparatory steps for locking the site and finally personal sign-off by the lead investigator at each site for that site's data. As you can see from the chart below, the shorts are already starting to get nervous. The Company's lead program is a 331-patient Phase III trial of DCVax®-L for newly diagnosed Glioblastoma multiforme (GBM). We are currently conducting a 348-patient double blind, randomized, placebo controlled Phase III clinical trial with DCVax-L for newly diagnosed GBM. This process continues to be impacted by the effects of COVID-19, especially with the resurgence of COVID cases in many areas. View original content to download multimedia:http://www.prnewswire.com/news-releases/northwest-biotherapeutics-announces-completion-of-phase-3-trial-sites-databases-301099438.html, © 1985 - 2021 BioSpace.com. The Company’s lead program is a 331-patient Phase III trial of DCVax®-L for newly diagnosed Glioblastoma multiforme (GBM). For example, key experts at certain specialized service providers have been unavailable for periods of time due to illness in their family. Finally, on Oct. 5, 2020, NWBO declared that data from the phase 3 study has been BETHESDA, Md., Oct. 5, 2020 /PRNewswire/ -- Northwest Biotherapeutics (OTCQB: NWBO) ("NW Bio"), a biotechnology company developing DCVax ® … After surgery and chemoradiotherapy, patients were randomized (2:1) to receive temozolomide plus DCVax-L (n = 232) or temozolomide and … The statisticians will proceed as quickly as possible with analyses of the raw data and prepare summaries of the Trial results for review by the Company, the Principal Investigator, the Steering Committee of the Trial, the Scientific Advisory Board, and a panel of independent brain cancer experts, who will analyze the data with the statisticians in preparation for public announcement and scientific publication. The shorts are about to be squeezed later this month in NWBO stock when the company will UNBLIND, UNVEIL, and ANNOUNCE, **finally,** the results of its THIRTEEN YEAR LONG PHASE THREE TRIAL OF DCVAX FOR GLIOBLASTOMA BRAIN CANCER. All three utilize dendritic cells, one of many types of white blood cells. The Company previously conducted a Phase I/II trial with DCVax-L for advanced ovarian cancer together with the University of Pennsylvania. Northwest Biotherapeutics is a biotechnology company focused on developing personalized immunotherapy products designed to treat cancers more effectively than current treatments, without toxicities of the kind associated with chemotherapies, and on a cost-effective basis, in both North America and Europe. Results for the phase 3 trial of DCVax-L in the treatment of newly diagnosed glioblastoma multiforme (ndGBM) should be released in late June or early July. When this external data joins the now locked data from the Trial sites, the overall Trial dataset will be locked. In anticipation, I wanted to reiterate why I believe there is a reasonable possibility for a successful outcome. Words such as “expect,” “believe,” “intend,” “design,” “plan,” “continue,” “may,” “will,” “anticipate,” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Powers continued. Powered by Madgex Job Board Software, http://www.prnewswire.com/news-releases/northwest-biotherapeutics-announces-completion-of-phase-3-trial-sites-databases-301099438.html. Statements made in this news release that are not historical facts, including statements concerning future treatment of patients using DCVax and future clinical trials, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. BETHESDA, Md., Sept. 1, 2020 /PRNewswire/ -- Northwest Biotherapeutics, Inc. (OTCQB: NWBO) ("NW Bio"), a biotechnology company developing DCVax ® personalized immune therapies for solid tumor cancers, today announced that the Company has acquired Flaskworks, a company that has developed a breakthrough system to close and automate the manufacturing of cell therapy products … NWBO indicated at ASCO in early June and reiterated in a presentation on September 1 that investigators in the trial are preparing a paper discussing unblinded data from the phase 3 trial. The Company previously conducted a Phase I/II trial with DCVax-L for advanced ovarian cancer together with the University of Pennsylvania. It is on the road to FDA approval as well as clinical trials throughout Europe. The Company has a broad platform technology for DCVax® dendritic cell-based vaccines. The sites' data includes all of the clinical data gathered in the Case Report Forms throughout the Trial, and now sit in a signed off, locked position with the CRO. The Company currently anticipates that the remaining analyses by these specialty service providers will be completed within the next couple weeks. Ken : How have NWBO’s clinical trials gone? The phase 3 trial of DCVax-L in newly diagnosed glioblastoma is continuing even though it has passed the 248 PFS events (mPFS is a primary endpoint) and has probably surpassed 233 OS events (mOS is an independent co-primary endpoint). For that purpose, the lead investigator must undergo training on the system, review the site data, personally complete the confirmation and deliver it to the independent contract research organization (CRO) managing the Trial. Specifically, there are a number of important factors that could cause actual results to differ materially from those anticipated, such as risks related to the Company's ability to enroll patients in its clinical trials and complete the trials on a timely basis, uncertainties about the clinical trials process, uncertainties about the timely performance of third parties, risks related to whether the Company's products will demonstrate safety and efficacy, risks related to the Company's ongoing ability to raise additional capital, and other risks included in the Company's Securities and Exchange Commission ("SEC") filings. The Company assumes no obligation to update any forward-looking statements as a result of new information, future events or developments, except as required by securities laws. Following completion of the Trial data lock, the independent statisticians will be given access to the raw data in the Trial database, and will undertake the calculations and the preparations of the Tables and Listings which provide the Trial results. Finally, there may be other factors not mentioned above or included in the Company's SEC filings that may cause actual results to differ materially from those projected in any forward-looking statement. The University of Pennsylvania but the data was still not unblinded //www.prnewswire.com/news-releases/northwest-biotherapeutics-announces-completion-of-phase-3-trial-sites-databases-301099438.html, © 1985 nwbo phase 3 2021 BioSpace.com out. For example, key experts at certain specialized service providers have been unavailable for periods of time due to Company. Advanced ovarian cancer together with the University of Pennsylvania been necessary to go back and obtain material! 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